The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...
Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...
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Mitotic stopwatch pathway shows how cancer loses its sense of time to avoid stress responses
When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example, DNA damage or chromosomal instability. That's why our cells come with an innate ...
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A starting signal for cell division: Molecular switch ensures that cells divide at the right time
About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...
A centromere is a specialized location in the DNA that functions as the control center of cell division and is maintained, unchanged, across generations of cells. It is characterized by a special ...
Researchers have found a molecular mechanism that prevents multiplication of potentially dangerous cells by measuring the duration of mitosis. They have shown that this mechanism -- the Mitotic ...
Research from Umeå University paves the way for a quantitative data analysis method to study the cell division process in individual cells. The improved resolution will promote advanced cell analysis ...
“We closed a gap in our knowledge that was open for 10 years,” says Duccio Conti, a postdoc in the Musacchio group and first author of the publication. In healthy DNA replication, at first, each new ...
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