A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

The human genome is no longer just a sequence to be read. It’s a dynamic structure that twists, folds, and reshapes itself in ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

Cancer isn't just about broken genes-it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off neighborhoods from essential services.

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...