The Denver Broncos lost their first game since September, and their first home game since October 2024, in a 34-20 defeat to the Jacksonville Jaguars on Sunday. We all knew it had to end eventually; and it is better Denver lost now than in the first round of the playoffs.

The Jacksonville Jaguars are one step closer to a playoff berth after defeating the Denver Broncos 34-20 in their most impressive showing of the year.

The AFC South-leading Jaguars (11-4) won their sixth straight game and handed the Broncos (12-3) their first loss since Week 3.

The AFC South-leading Jaguars (11-4) won their sixth straight game and handed the Broncos (12-3) their first loss since Week 3. It was also Denver's first loss at home since Oct. 13, 2024, snapping the Broncos' 12-game home winning streak.

Kickoff is 4:05 p.m. on Sunday, Dec. 21. The Jaguars achieved one of their best all-around performances last week against the Jets, tying franchise records for touchdown passes ( Trevor Lawrence with five) and touchdown receptions ( Travis Etienne with three ).

The Jacksonville Jaguars snapped the Denver Broncos ' 11-game winning streak on Sunday with a 34-20 upset win at Empower Field at Mile High. Jacksonville improved to 11-4 with the victory and Denver dropped to 12-3.

The Broncos are 3.5-point favorites in the latest Jaguars vs. Broncos odds at DraftKings, and the total comes in at 46.5. The Broncos are -180 money line favorites (risk $180 to win $100), while the Jags are +150 underdogs.

The Denver Broncos (12-3) lost to the Jacksonville Jaguars (11-4) in Week 16 of the 2025 NFL season at Empower Field at Mile High on Sunday afternoon. Despite the 34-20 loss, Denver still has a chance to win the AFC West and claim the conference's No.