One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

Rosalind Franklin’s role in the discovery of the structure of DNA may have been different than previously believed. Franklin wasn’t the victim of data theft at the hands of James Watson and Francis ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

A dissertation study at the University of Jyväskylä (Finland) developed two-dimensional fishnet-like structures from DNA ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...