Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells—an advance ...

RNA is usually portrayed as a molecule that works deep inside the cell, helping to turn genetic information into proteins.

HIV infects immune cells and establishes long-lasting infections that can progress to acquired immunodeficiency syndrome (AIDS) if left untreated. With the advancement of antiviral therapy (ART), HIV ...

Balancing the immune system is a delicate act. If it’s too weak, infections and cancer can take hold; if it’s too strong, autoimmune diseases or transplant rejection can occur. Researchers have ...

In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR ...

Chemotherapy drugs that target cancer cells without damaging normal cells remain one of the key goals of precision medicine ...

A new method can produce specially designed proteins that can arm T cells to attack cancer cells. Precision personalized cancer treatment on a larger scale has come a step closer after researchers ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...

In a potentially major breakthrough for regenerative medicine, scientists at MIT have developed a way to convert skin cells directly into brain cells extremely efficiently, without needing to go ...